Document Detail

Birth-cohort analysis of peptic ulcer mortality in Europe.
MedLine Citation:
PMID:  3998048     Owner:  NLM     Status:  MEDLINE    
The age- and sex-specific death rates of gastric and duodenal ulcer are followed in eight European countries over a period ranging from 30 to 60 yr. A cohort analysis demonstrates that the temporal changes of peptic ulcer mortality in the European countries seem to occur in a fashion characteristic of those due to changes in birth-cohort risks. Generations born at the end of the 19th century manifested a high risk of dying from gastric and duodenal ulcer. The birth-cohorts with a high risk for duodenal ulcer lagged 10-30 yr behind those with a high risk for gastric ulcer. Male and female cohorts with the highest risk were born at the same time. The birth-cohort phenomenon is most obvious in male death rates of gastric and duodenal ulcer. A birth-cohort phenomenon would imply that important determinants for the development of gastric and duodenal ulcer occur early in the life of a cohort and that it is these early determinants that are changing with time. The determinants could be environmental factors which interact with the pathophysiology of peptic ulcer from the outside.
A Sonnenberg; H Müller; F Pace
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of chronic diseases     Volume:  38     ISSN:  0021-9681     ISO Abbreviation:  J Chronic Dis     Publication Date:  1985  
Date Detail:
Created Date:  1985-07-08     Completed Date:  1985-07-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985123R     Medline TA:  J Chronic Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  309-17     Citation Subset:  IM    
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MeSH Terms
Age Factors
Duodenal Ulcer / mortality*
Germany, West
Middle Aged
Sex Factors
Stomach Ulcer / mortality*

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