Document Detail


Birth-cohort analysis of peptic ulcer mortality in Europe.
MedLine Citation:
PMID:  3998048     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The age- and sex-specific death rates of gastric and duodenal ulcer are followed in eight European countries over a period ranging from 30 to 60 yr. A cohort analysis demonstrates that the temporal changes of peptic ulcer mortality in the European countries seem to occur in a fashion characteristic of those due to changes in birth-cohort risks. Generations born at the end of the 19th century manifested a high risk of dying from gastric and duodenal ulcer. The birth-cohorts with a high risk for duodenal ulcer lagged 10-30 yr behind those with a high risk for gastric ulcer. Male and female cohorts with the highest risk were born at the same time. The birth-cohort phenomenon is most obvious in male death rates of gastric and duodenal ulcer. A birth-cohort phenomenon would imply that important determinants for the development of gastric and duodenal ulcer occur early in the life of a cohort and that it is these early determinants that are changing with time. The determinants could be environmental factors which interact with the pathophysiology of peptic ulcer from the outside.
Authors:
A Sonnenberg; H Müller; F Pace
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of chronic diseases     Volume:  38     ISSN:  0021-9681     ISO Abbreviation:  J Chronic Dis     Publication Date:  1985  
Date Detail:
Created Date:  1985-07-08     Completed Date:  1985-07-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985123R     Medline TA:  J Chronic Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  309-17     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Aged
Denmark
Duodenal Ulcer / mortality*
Female
France
Germany, West
Humans
Ireland
Italy
Male
Middle Aged
Netherlands
Risk
Scotland
Sex Factors
Spain
Stomach Ulcer / mortality*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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