Document Detail

Birth characteristics of different ocular congenital abnormalities in hungary.
MedLine Citation:
PMID:  16854769     Owner:  NLM     Status:  MEDLINE    
AIMS: The aim of the study was to estimate the prevalence at birth of different ocular congenital abnormalities and to describe their birth characteristics in Hungary. METHODS: Two data sets were evaluated: the national-based Hungarian Congenital Abnormality Registry and the Hungarian Case-Control Surveillance of Congenital Abnormalities which include cases with ocular abnormalities and patient controls with other (non-ocular) congenital abnormalities, and population controls without abnormalities from the National Birth Registry. RESULTS: Seven hundred twelve cases were found with ocular abnormalities in the data set of the Hungarian Congenital Abnormality Registry (2.62 per 10,000 live births), while that of the Hungarian Case-Control Surveillance of Congenital Abnormalities included 314 cases with ocular defects among 2.7 million live births in Hungary between 1980 and 2002. There was an obvious underascertainment and/or notification of cases with ocular defects because an extra effort to ascertain all cases with ocular abnormalities resulted in a birth prevalence of 6.31 per 10,000 live births in 1999. The main birth characteristics of cases were male excess, shorter mean gestational age and smaller mean birth weight with a larger proportion of preterm birth and low birthweight. CONCLUSIONS: Earlier diagnosis of ocular abnormalities is necessary with a more complete notification of these cases to the Hungarian Congenital Abnormality Registry. The birth characteristics of cases with ocular abnormalities may have some associations with the origin of ocular defects; therefore, these variables will require further studies in case-control approach.
Gábor Vogt; Melinda Szunyogh; Andrew E Czeizel
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Ophthalmic epidemiology     Volume:  13     ISSN:  0928-6586     ISO Abbreviation:  Ophthalmic Epidemiol     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-07-20     Completed Date:  2006-08-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9435674     Medline TA:  Ophthalmic Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  159-66     Citation Subset:  IM    
Hospital and Central Outpatients Clinics of the Hungarian State Railways, Budapest, Hungary.
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MeSH Terms
Birth Weight*
Eye Abnormalities / epidemiology*
Gestational Age*
Hungary / epidemiology
Infant, Newborn
Population Surveillance*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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