| Birth after double cryopreservation of human oocytes at metaphase II and pronuclear stages. | |
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MedLine Citation:
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PMID: 16500354 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To document the possibility to double-cryopreserve human metaphase II and pronuclear oocytes. DESIGN: Case report. SETTING: University-based IVF center. PATIENT(S): A couple with primary andrological infertility. INTERVENTION(S): Pronuclear stage oocytes derived after sperm injection into frozen-thawed metaphase II oocytes were cryopreserved again for later transfer. MAIN OUTCOME MEASURE(S): Post-thaw survival rates and pregnancy. RESULT(S): Five metaphase II oocytes survived the freeze-thaw procedure. Three of five oocytes presented with two pronuclei after sperm injection and were cryopreserved again. Post-thawing, all three oocytes developed into good quality embryos for transfer. A singleton pregnancy was achieved, resulting in the birth of a healthy girl. CONCLUSION(S): Double-cryopreservation of oocytes at metaphase II and at pronuclear stage is a treatment option in human-assisted reproduction. |
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Authors:
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Markus Montag; Katrin van der Ven; Christoph Dorn; Vladimir Isachenko; Eugenia Isachenko; Hans van der Ven |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 85 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2006 Mar |
Date Detail:
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Created Date: 2006-02-27 Completed Date: 2006-03-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 751.e5-751.e7 Citation Subset: IM |
Affiliation:
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Department of Gynecological Endocrinology and Reproductive Medicine, University of Bonn, Bonn, Germany. Markus.Montag@ukb.uni-bonn.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cryopreservation* Embryo Transfer Female Humans Infant, Newborn Male Metaphase* Oocytes / cytology* Parturition* Pregnancy Prophase* Sperm Injections, Intracytoplasmic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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