Document Detail

Birth outcomes following self-inflicted poisoning during pregnancy, California, 2000 to 2004.
MedLine Citation:
PMID:  21585527     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe birth outcomes following intentional acute poisoning during pregnancy.
SETTING: California Linked Vital Statistics-Patient Discharge Database, 2000 to 2004.
PARTICIPANTS: Pregnant women age 15 to 44, who had a singleton live birth or fetal death that occurred between gestational ages 20 and 42 weeks who were discharged from the hospital for an intentional poisoning were compared to pregnant women discharged from the hospital for any nonpoisoning diagnosis. Intentional acute poisoning hospital discharges were identifed by the presence of an ICD-9-CM E-Codes E950-E952 (suicide, attempted suicide and self-inflicted injuries specified as intentional.)
METHODS: Through a retrospective cohort design, birth outcomes including low birth weight; preterm birth; fetal, neonatal, and infant death; and congenital anomalies were identified by the presence of ICD-9-CM diagnosis codes or by notation in the dataset.
RESULTS: There were 430 hospital discharges for an intentional poisoning during pregnancy documented in the dataset (rate=25.87/100,000 person years). The rate of intentional poisoning was greatest in the first weeks of gestation and declined with increasing gestational age. Analgesics, antipyretics, and antirheumatics were most commonly implicated. Adverse birth outcomes associated with intentional poisoning included preterm birth (odds ratio [OR]=1.34; 95% Confidence Interval [CI] [1.01, 1.77]), low birth weight (OR=1.49; 95% CI [1.04, 2.12]), and circulatory system congenital anomalies (OR=2.17; 95% CI [1.02, 4.59]).
CONCLUSION: Intentional acute poisoning during pregnancy was associated with several adverse birth outcomes; however, these relationships may be confounded by concomitant maternal substance abuse.
Candace K McClure; Thelma E Patrick; Kenneth D Katz; Sheryl F Kelsey; Harold B Weiss
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of obstetric, gynecologic, and neonatal nursing : JOGNN / NAACOG     Volume:  40     ISSN:  1552-6909     ISO Abbreviation:  J Obstet Gynecol Neonatal Nurs     Publication Date:    2011 May-Jun
Date Detail:
Created Date:  2011-05-18     Completed Date:  2011-09-20     Revised Date:  2012-03-02    
Medline Journal Info:
Nlm Unique ID:  8503123     Medline TA:  J Obstet Gynecol Neonatal Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  292-301     Citation Subset:  IM; N    
Copyright Information:
© 2011 AWHONN, the Association of Women's Health, Obstetric and Neonatal Nurses.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
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MeSH Terms
Attitude to Health
California / epidemiology
Cohort Studies
Confidence Intervals
Maternal Welfare / statistics & numerical data*
Mothers / psychology*,  statistics & numerical data
Odds Ratio
Patient Admission / statistics & numerical data
Patient Discharge / statistics & numerical data
Poisoning / epidemiology*,  psychology
Pregnancy Outcome / epidemiology*,  psychology
Retrospective Studies
Self Concept*
Self-Injurious Behavior / epidemiology*,  psychology
Stress, Psychological / epidemiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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