| Bipolar mood disorder: practical strategies for acute and maintenance phase treatment. | |
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MedLine Citation:
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PMID: 8707998 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The chronic, complex, and episodic course of bipolar mood disorder presents a formidable challenge to the clinician making a treatment plan. Although numerous therapeutic agents are reported to be efficacious for one or more aspects of bipolar illness, treatment is seldom completely effective and is never curative. The goal of treatment is to modify the symptomatic expression of the illness with the result that fewer, briefer, and milder episodes occur. In pursuit of this goal, the use of multiple medications, polypharmacy, is the rule rather than the exception. This article offers recommendations for treatment strategies based on the phase and stage of the illness. The strategies are organized into algorithms that emphasize the use of mood-stabilizing medications as initial steps in a systematic, iterative approach to treatment. Practical issues related to the use of mood-stabilizing therapies are discussed. |
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Authors:
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G S Sachs |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of clinical psychopharmacology Volume: 16 ISSN: 0271-0749 ISO Abbreviation: J Clin Psychopharmacol Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1996-09-11 Completed Date: 1996-09-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8109496 Medline TA: J Clin Psychopharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 32S-47S Citation Subset: IM |
Affiliation:
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Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Anticonvulsants / administration & dosage, adverse effects Antimanic Agents / administration & dosage*, adverse effects Bipolar Disorder / classification, drug therapy*, psychology Carbamazepine / administration & dosage, adverse effects Clinical Trials as Topic Combined Modality Therapy Drug Therapy, Combination Female Humans Infant, Newborn Long-Term Care Male Pregnancy Psychotropic Drugs / administration & dosage*, adverse effects Treatment Outcome Valproic Acid / administration & dosage, adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Antimanic Agents; 0/Psychotropic Drugs; 298-46-4/Carbamazepine; 99-66-1/Valproic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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