Document Detail


Bipolar disorder and metabolic syndrome: comorbidity or side effects of treatment of bipolar disorder.
MedLine Citation:
PMID:  20305595     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: There is evidence that people with mental disorders are more likely to suffer from metabolic syndrome. In the last decades there has been an increase in interest for researching metabolic syndrome in psychiatric patients and plenty of evidence about their association. However, investigations on the prevalence of metabolic syndrome in patients with bipolar disorder are still surprisingly rare. The aim of this paper is to analyze comorbidity of bipolar disorder and metabolic syndrome, and the association of treatment with antipsychotics and mood stabilizers with metabolic syndrome, as well as to point out the necessity of appropriate preventive measures and treatment of metabolic syndrome in patient with bipolar disorder.
CONTENT ANALYSIS OF LITERATURE: Literature research included structured searches of Medline and other publications on the subject of comorbidity of bipolar disorder and metabolic syndrome, and the association of treatment with antipsychotics and mood stabilizers with metabolic syndrome, as well as preventive measures and treatment of metabolic syndrome in patient with bipolar disorder.
CONCLUSION: Metabolic syndrome is present in 8-56% of patients suffering from bipolar disorder. Metabolic syndrome in patients with bipolar disorder can significantly contribute to morbidity and mortality, and it is certainly necessary to think of it, to take adequate preventive and therapeutic measures in treating its individual components. Further investigation on association between bipolar disorder and metabolic disorder, and the association of treatment with antipsychotics and mood stabilizers with metabolic syndrome are necessary.
Authors:
Dragan Babić; Boris Maslov; Marko Martinac; Katica Nikolić; Suzana Uzun; Oliver Kozumplik
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Psychiatria Danubina     Volume:  22     ISSN:  0353-5053     ISO Abbreviation:  Psychiatr Danub     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-23     Completed Date:  2010-10-08     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  9424753     Medline TA:  Psychiatr Danub     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, School of Medicine, University of Mostar, Bosnia and Herzegovina. dragan.babic@tel.net.ba
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MeSH Terms
Descriptor/Qualifier:
Anticonvulsants / adverse effects*,  therapeutic use
Antipsychotic Agents / adverse effects*,  therapeutic use
Bipolar Disorder / drug therapy*,  epidemiology
Comorbidity
Cross-Sectional Studies
Humans
Metabolic Syndrome X / chemically induced*,  diagnosis,  epidemiology
Risk Factors
Chemical
Reg. No./Substance:
0/Anticonvulsants; 0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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