| Bipolar course in schizo-affective illness. | |
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MedLine Citation:
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PMID: 971445 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors undertook a chart review to examine the use of the diagnosis of schizophrenia, schizo-affective type, in clinical practice. Of 27 patients given this diagnosis over a 3-year period, 13 were found to have evidence of bipolar course in their illnesses. For both the bipolar and unipolar groups, the most striking finding in first-degree relatives was the prominence of affective conditions. The bipolar group had a statistically significant earlier age for first psychiatric treatment and previous number of hospitalizations. Symptoms noted on admission were mostly affective, and the schizophrenic symptoms reported were noted by authors to be considered overinclusive or unreliable by many clinicians. Both groups received treatment with antipsychotic and antidepressant medication. Six of 13 bipolar patients and no unipolar patients were treated with lithium carbonate. Five bipolar patients met research criteria of Feighner et al. (1972) for primary affective illness and another met the criteria for schizophreniform illness. One unipolar patient met criteria for probable primary affective illness and another met the criteria for probable schizophreniform illness. The authors concluded that the diagnosis of schizo-affective illness, as used in day to day clinical practice, does not identify a group of schizophrenic patients nor a homogeneous patient group, and when both affective and schizophrenic features appear in a patient with a bipolar illness, the diagnosis of manic-depressive illness, not schizophrenia, should be given first consideration. |
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Authors:
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R D Sovner; P R McHugh |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biological psychiatry Volume: 11 ISSN: 0006-3223 ISO Abbreviation: Biol. Psychiatry Publication Date: 1976 Apr |
Date Detail:
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Created Date: 1976-12-03 Completed Date: 1976-12-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0213264 Medline TA: Biol Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 195-204 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Affective Symptoms / genetics Age Factors Antidepressive Agents / therapeutic use Bipolar Disorder / diagnosis*, drug therapy Child Diagnosis, Differential Female Hospitalization Humans Lithium / therapeutic use Male Schizophrenia / diagnosis* Tranquilizing Agents / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antidepressive Agents; 0/Tranquilizing Agents; 7439-93-2/Lithium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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