Document Detail


Biphasic change in correlation between ovarian lipid peroxides and progestational activity during pseudopregnancy induced in immature rats.
MedLine Citation:
PMID:  10535510     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We measured ovarian lipid peroxide (LP) levels and plasma progestins, progesterone (P4) and 20alpha-dihydroprogesterone, throughout pseudopregnancy in gonadotropin-primed immature rats. Plasma P4 fluctuated, with two peaks on days 5 (PSP5) and 8 of pseudopregnancy, and then declined to the basal level by PSP12. Ovarian LP increased from PSP1 to PSP4, decreased temporarily until PSP8, and then rose gradually until PSP14. From PSP1 through PSP7, ovarian LP was positively correlated with total progestins according to the Spearman ranked correlation coefficient (r=+0.829, p<0.05). In contrast, a negative correlation between ovarian LP and plasma P4 was apparent (r=-0.816, p<0.05) from PSP8 to PSP14. These results show the biphasic correlation of LP with luteal progestational activity depending on the luteal stage.
Authors:
S Kurusu; K Tsukamoto; H Konishi; M Tachibana; M Kawaminami; I Hashimoto
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  61     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-11-18     Completed Date:  1999-11-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1039-42     Citation Subset:  IM    
Affiliation:
Laboratory of Veterinary Physiology, Kitasato University School of Veterinary Medicine and Animal Sciences, Towada, Aomori, Japan.
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MeSH Terms
Descriptor/Qualifier:
20-alpha-Dihydroprogesterone / blood
Animals
Chorionic Gonadotropin / physiology
Female
Lipid Peroxides / analysis,  physiology*
Luteal Phase / physiology
Malondialdehyde / analysis
Ovary / physiology*
Ovulation
Pregnancy
Progesterone / blood
Progestins / blood*
Pseudopregnancy / physiopathology,  veterinary*
Radioimmunoassay / veterinary
Rats
Rats, Wistar
Statistics, Nonparametric
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Lipid Peroxides; 0/Progestins; 145-14-2/20-alpha-Dihydroprogesterone; 542-78-9/Malondialdehyde; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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