Document Detail


Biosynthesis and uptake of siderophores is controlled by the PacC-mediated ambient-pH Regulatory system in Aspergillus nidulans.
MedLine Citation:
PMID:  15075286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biosynthesis and uptake of siderophores in Aspergillus nidulans are regulated not only by iron availability but also by ambient pH: expression of this high-affinity iron uptake system is elevated by an increase in the ambient pH. Mediation of this regulation by the transcriptional regulator PacC has been confirmed via acidity- and alkalinity-mimicking mutants.
Authors:
Martin Eisendle; Harald Oberegger; Rudolf Buttinger; Paul Illmer; Hubertus Haas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Eukaryotic cell     Volume:  3     ISSN:  1535-9778     ISO Abbreviation:  Eukaryotic Cell     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-04-12     Completed Date:  2004-12-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  101130731     Medline TA:  Eukaryot Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  561-3     Citation Subset:  IM    
Affiliation:
Department of Molecular Biology, Medical University of Innsbruck, Austria.
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MeSH Terms
Descriptor/Qualifier:
Aspergillus nidulans / genetics,  metabolism*
Fungal Proteins / genetics,  metabolism,  physiology*
Gene Expression Regulation, Fungal / genetics
Hydrogen-Ion Concentration
Iron / metabolism
Mutation
Siderophores / biosynthesis,  genetics,  metabolism*
Transcription Factors / genetics,  metabolism,  physiology*
Chemical
Reg. No./Substance:
0/Fungal Proteins; 0/PacC protein, Aspergillus; 0/Siderophores; 0/Transcription Factors; 7439-89-6/Iron
Comments/Corrections

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