| Biosynthesis of prostaglandin E2 and F2 alpha in gingiva of patients with chronic periodontitis. | |
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MedLine Citation:
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PMID: 6937509 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The biosynthesis of radioactive prostaglandin E2 (PGE2) and F2 alpha from (1-14C) arachidonic acid has been demonstrated in the microsomal fraction of gingiva of patients with chronic periodontitis in vitro. 14C corresponding to unmetabolized arachidonic acid in three separate incubations was 83, 66, and 83%, and that corresponding to both PGE2 and PGF2 alpha was 8, 22, and 9% of the total radioactivity recovered after chromatography. The ratios of PGE2 to PGF2 alpha were found to be 6:1, 6:1, and 3:1, respectively. |
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Authors:
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T M Elattar; H S Lin |
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Publication Detail:
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Type: In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of dental research Volume: 60 ISSN: 0022-0345 ISO Abbreviation: J. Dent. Res. Publication Date: 1981 Mar |
Date Detail:
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Created Date: 1981-05-13 Completed Date: 1981-05-13 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0354343 Medline TA: J Dent Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 748-50 Citation Subset: D; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arachidonic Acids
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metabolism Gingiva / metabolism* Humans Microsomes / metabolism Periodontitis / metabolism* Prostaglandins E / biosynthesis* Prostaglandins F / biosynthesis* |
| Grant Support | |
ID/Acronym/Agency:
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DE-04276-03/DE/NIDCR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Arachidonic Acids; 0/Prostaglandins E; 0/Prostaglandins F |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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