Document Detail


Biosynthesis of prostaglandin E2 and F2 alpha in gingiva of patients with chronic periodontitis.
MedLine Citation:
PMID:  6937509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The biosynthesis of radioactive prostaglandin E2 (PGE2) and F2 alpha from (1-14C) arachidonic acid has been demonstrated in the microsomal fraction of gingiva of patients with chronic periodontitis in vitro. 14C corresponding to unmetabolized arachidonic acid in three separate incubations was 83, 66, and 83%, and that corresponding to both PGE2 and PGF2 alpha was 8, 22, and 9% of the total radioactivity recovered after chromatography. The ratios of PGE2 to PGF2 alpha were found to be 6:1, 6:1, and 3:1, respectively.
Authors:
T M Elattar; H S Lin
Related Documents :
10699749 - Altered eicosanoid biosynthesis in selenium-deficient endothelial cells.
10810449 - Ebselen as a peroxynitrite scavenger in vitro and ex vivo.
6354779 - Endogenous prostaglandin synthesis and glucose-induced insulin secretion from the adult...
15650409 - The cyclopentenone (a2/j2) isoprostanes--unique, highly reactive products of arachidona...
1906619 - Inhibition of rabbit erythroid 15-lipoxygenase and sheep vesicular gland prostaglandin ...
2880609 - Microtubule disruption enhances prostaglandin e2 production in osteoblastic cells.
4039149 - The effect of coenzyme q10 on the action of phospholipase.
10600639 - Characterization of plasma unsaturated lysophosphatidylcholines in human and rat.
1691599 - Determination of dityrosine, phosphotyrosine, phosphothreonine, and phosphoserine by hi...
Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of dental research     Volume:  60     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  1981 Mar 
Date Detail:
Created Date:  1981-05-13     Completed Date:  1981-05-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  748-50     Citation Subset:  D; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Arachidonic Acids / metabolism
Gingiva / metabolism*
Humans
Microsomes / metabolism
Periodontitis / metabolism*
Prostaglandins E / biosynthesis*
Prostaglandins F / biosynthesis*
Grant Support
ID/Acronym/Agency:
DE-04276-03/DE/NIDCR NIH HHS
Chemical
Reg. No./Substance:
0/Arachidonic Acids; 0/Prostaglandins E; 0/Prostaglandins F

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Secretion of monovalent ions and water in ferret salivary glands: a micropuncture study.
Next Document:  The laser-Raman spectroscopic studies on human enamel and precipitated carbonate-containing apatites...