| Biosynthesis of abscisic acid by the direct pathway via ionylideneethane in a fungus, Cercospora cruenta. | |
| | |
MedLine Citation:
|
PMID: 15618629 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We examined the biosynthetic pathway of abscisic acid (ABA) after isopentenyl diphosphate in a fungus, Cercospora cruenta. All oxygen atoms at C-1, -1, -1', and -4' of ABA produced by this fungus were labeled with (18)O from (18)O(2). The fungus did not produce the 9Z-carotenoid possessing gamma-ring that is likely a precursor for the carotenoid pathway, but produced new sesquiterpenoids, 2E,4E-gamma-ionylideneethane and 2Z,4E-gamma-ionylideneethane, along with 2E,4E,6E-allofarnesene. The fungus converted these sesquiterpenoids labeled with (13)C to ABA, and the incorporation ratio of 2Z,4E-gamma-ionylideneethane was higher than that of 2E,4E-gamma-ionylideneethane. From these results, we concluded that C. cruenta biosynthesized ABA by the direct pathway via oxidation of ionylideneethane with molecular oxygen following cyclization of allofarnesene. This direct pathway via ionylideneethane in the fungus is consistent with that in Botrytis cinerea, except for the positions of double bonds in the rings of biosynthetic intermediates, suggesting that the pathway is common among ABA-producing fungi. |
| | |
Authors:
|
Masahiro Inomata; Nobuhiro Hirai; Ryuji Yoshida; Hajime Ohigashi |
Related Documents
:
|
9925739 - 2,6-difluorophenol as a bioisostere of a carboxylic acid: bioisosteric analogues of gam... 19434509 - Seed-specific expression of truncated osgad2 produces gaba-enriched rice grains that in... 6279829 - Fluctuation analysis of neutral amino acid responses in cultured mouse spinal neurones. 18586049 - Conantokin-p, an unusual conantokin with a long disulfide loop. 7145039 - The in vitro inhibition of gaba release by tetanus toxin. 12696919 - Metabolite profiling of tomato (lycopersicon esculentum) using 1h nmr spectroscopy as a... 20108009 - Synthesis of 2-azaspiro[3.3]heptane-derived amino acids: ornitine and gaba analogues. 9084179 - Influence of bacillus subtilis phor on cell wall anionic polymers. 1368809 - Fumaric acid production from hydrolysates of starch-based substrates. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Bioscience, biotechnology, and biochemistry Volume: 68 ISSN: 0916-8451 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2004 Dec |
Date Detail:
|
Created Date: 2004-12-24 Completed Date: 2005-06-21 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
|
Languages: eng Pagination: 2571-80 Citation Subset: IM |
Affiliation:
|
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abscisic Acid
/
analogs & derivatives*,
biosynthesis*,
metabolism* Carotenoids / metabolism Cyclization Fungi / metabolism* Mevalonic Acid / metabolism Oxygen / metabolism Sesquiterpenes / metabolism |
| Chemical | |
Reg. No./Substance:
|
0/Sesquiterpenes; 0/ionylideneethane; 150-97-0/Mevalonic Acid; 21293-29-8/Abscisic Acid; 36-88-4/Carotenoids; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: N-linked glycan structures of human lactoferrin produced by transgenic rice.
Next Document: Identification of three clones which commonly interact with the kinase domains of highly homologous ...