| Biosynthesis of 20-hydroxyecdysone in Ajuga hairy roots: the possibility of 7-ene introduction at a late stage. | |
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MedLine Citation:
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PMID: 10783979 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Administration of [3alpha-2H]-3beta-hydroxy-5beta-cholestan-6-one to hairy roots of Ajuga reptans var. atropurpurea followed by 2H-NMR spectroscopic analysis of the resulting 20-hydroxyecdysone so formed revealed that the substrate was efficiently incorporated into the latter. Additionally, [5beta,7alpha,7beta-2H3]-2beta,3beta-dihydroxy-+ ++5beta-cholestan-6-one was converted into 20-hydroxyecdysone. These findings clearly indicate that Ajuga hairy roots are capable of introducing a double bond at the 7-position at a late stage of 20-hydroxyecdysone biosynthesis, suggesting the possibility of an alternative biosynthetic pathway which does not involve 7-dehydrocholesterol as an obligatory intermediate. |
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Authors:
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R Hyodo; Y Fujimoto |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Phytochemistry Volume: 53 ISSN: 0031-9422 ISO Abbreviation: Phytochemistry Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-07-25 Completed Date: 2000-07-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0151434 Medline TA: Phytochemistry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 733-7 Citation Subset: IM |
Affiliation:
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Department of Chemistry and Materials Science, Tokyo Institute of Technology, Meguro, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ecdysterone
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biosynthesis*,
chemistry Magnetic Resonance Spectroscopy Mass Spectrometry Plant Roots / metabolism* |
| Chemical | |
Reg. No./Substance:
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5289-74-7/Ecdysterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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