| Biosynthesis of [1-15N] L-tryptophan from 15N labeled anthranilic acid by fermentation of Candida utilis mutant. | |
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MedLine Citation:
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PMID: 18235989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A new method for synthesizing the labeled L-tryptophan is described in this work. L-tryptophan, labeled with 98% (15)N at position 1 was synthesized from the labeled anthranilic acid using Candida utilis mutants. The conversion ratio of (15)N of 50% was achieved. The labeled anthranilic acid was synthesized by [(15)N] phthalimide that was prepared by 99.34% [(15)N] urea and phthalic anhydride in ortho-xylene medium at 140 degrees C and under atmospheric pressure. |
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Authors:
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Zhanfeng Liu; Qipeng Yuan; Wenchuan Wang |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-01-31 |
Journal Detail:
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Title: Amino acids Volume: 36 ISSN: 1438-2199 ISO Abbreviation: Amino Acids Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2009-01-06 Completed Date: 2009-03-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9200312 Medline TA: Amino Acids Country: Austria |
Other Details:
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Languages: eng Pagination: 71-3 Citation Subset: IM |
Affiliation:
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College of Life Science and Technology, Beijing University of Chemical Technology, P. O. Box 75, 100029, Beijing, People's Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anthranilic Acids
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chemistry,
metabolism* Candida / genetics, metabolism* Molecular Structure Mutation / genetics Nitrogen Isotopes Tryptophan / biosynthesis*, chemistry |
| Chemical | |
Reg. No./Substance:
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0/Anthranilic Acids; 0/Nitrogen Isotopes; 118-92-3/anthranilic acid; 73-22-3/Tryptophan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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