Document Detail


Bioresorbable everolimus-eluting vascular scaffold in patients with ST-segment elevation myocardial infarction: Optical coherence tomography evaluation and clinical outcomes.
MedLine Citation:
PMID:  25428734     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Bioresorbable vascular scaffold (BVS) implantation is a new, promising treatment method of coronary artery disease (CAD). Preliminary data in patients with stable angina is encouraging. However, the utility of BVS was not sufficiently evaluated in the setting of acute thrombotic lesions. The aim of this study was an optical coherence tomography (OCT) assessment of acute procedural result of the everolimus-eluting BVS implantation in patients with ST segment elevation myocardial infarction (STEMI) and evaluation of mid-term clinical outcomes.
METHODS: OCT examination was conducted in 23 STEMI patients who underwent primary angioplasty with BVS implantation. Off-line qualitative and quantitative coronary angiography (QCA) and OCT analyses were performed by an independent core laboratory.
RESULTS: Procedural and clinical success were achieved in 95.7% of patients, and device success was observed in all patients. In post-PCI OCT evaluation, most of the struts (95.4±7.96%) were well apposed, 4.6±5.71% were classified as malapposed. The final minimum lumen diameter was 2.6±0.35 mm, minimum scaffold area was 6.9±1.54 mm² and final residual stenosis was 8.8±24.37%. Edge dissections were found in 3 lesions (7.7%). Median follow-up period was 229 (IR 199-248) days. One myocardial infarction, due to sub-acute stent thrombosis, occurred in a patient who discontinued pharmacotherapy.
CONCLUSIONS: The study shows that everolimus-eluting BVS implantation in STEMI is safe and feasible. The OCT evaluation confirmed excellent acute performance with appropriate scaffold expansion and low rate of malapposition.
Authors:
Janusz Kochman; Mariusz Tomaniak; Arkadiusz Pietrasik; Lukasz Kołtowski; Adam Rdzanek; Zenon Huczek; Tomasz Mazurek; Jacek Jąkała; Aldona Ząbek; Jacek Legutko; Wacław Kochman; Krzysztof J Filipiak
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-27
Journal Detail:
Title:  Cardiology journal     Volume:  -     ISSN:  1897-5593     ISO Abbreviation:  Cardiol J     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-11-27     Completed Date:  -     Revised Date:  2014-11-28    
Medline Journal Info:
Nlm Unique ID:  101392712     Medline TA:  Cardiol J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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