Document Detail

Bioreactor for mammalian cell culture.
MedLine Citation:
PMID:  2510474     Owner:  NLM     Status:  MEDLINE    
Purpose of this article is to review the current status of bioreactor design for mammalian cell culture. Morphological and biochemical features of two major mammalian cell groups, anchorage-dependent and independent cells are proposed as a basis for different behavior at their cultivation. Different bioreactor configurations are systematically discussed through enumerating elementary physical phenomena and through stressing their physiological significance. Special considerations are given to those areas which are inherent to mammalian cell bioreactor.
A Prokop; M Z Rosenberg
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in biochemical engineering/biotechnology     Volume:  39     ISSN:  0724-6145     ISO Abbreviation:  Adv. Biochem. Eng. Biotechnol.     Publication Date:  1989  
Date Detail:
Created Date:  1989-11-27     Completed Date:  1989-11-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8307733     Medline TA:  Adv Biochem Eng Biotechnol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  29-71     Citation Subset:  IM; S    
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MeSH Terms
Cells, Cultured* / metabolism,  ultrastructure
Culture Media
Cytological Techniques / instrumentation*
Oxygen Consumption
Stress, Mechanical
Reg. No./Substance:
0/Culture Media

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