| Biopsy from the base and edge of gastric ulcer healing or complete healing may lead to detection of gastric cancer earlier: an 8 years endoscopic follow-up study. | |
| | |
MedLine Citation:
|
PMID: 22469743 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Background/Aims: To assess the incidence of gastric cancer development in gastric benign ulcer patients and to evaluate the value of biopsy by taking specimens from both the base and edges of ulcers in contrast to the traditional biopsy which takes specimens from the edges of ulcers only. Methodology: An endoscopic followup of more than 1 year was conducted on 456 gastric ulcer patients in our hospital for a duration over 8 years. We collected clinical, endoscopic and pathological data and obtained at least 6 biopsies from both the edges and the bases of ulcers healing or complete healing, respectively and assessed H. pylori infection. Results: Gastric cancers developed in 11 (2.41%) of 456 GU patients. In the experimental group, 3 cases that were diagnosed by histology showed adenocarcinoma with specimens taken from the ulcer bases and in the other 5 cases the specimens were taken from the ulcer edges. The detection rate of gastric cancer from gastric ulcer between experimental group and control group was statistically significant (4.57% vs. 1.07%, p<0.05). Conclusions: Gastric ulcer may develop into gastric cancer over a certain period of time in patients infected with H. pylori. Biopsies from ulcer bases and edges at the second or subsequent endoscopies may lead to defection of gastric cancer earlier and more effectively than the biopsies which take specimens from the edges of ulcers only. |
| | |
Authors:
|
Sheng-Xiang Lv; Jian-He Gan; Xing-Gang Ma; Chang-Cheng Wang; Hong-Mei Chen; Er-Ping Luo; Xiao-Ping Huang; Shao-Hong Wu; Ai-Lan Qin; Ke-Chen; Xiao-Hong Wang; Wei-Sun; Li-Chen; Ying-Xie; Feng-Xia Hu; Dan-Niu; Sarika Walia; Jian Zhu |
Related Documents
:
|
21799333 - State-level cancer quality assessment and research: building and sustaining the data in... 1754213 - Functional voice disorders. 19491683 - Ocular complications of cancer therapy: a primer for the ophthalmologist treating cance... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Hepato-gastroenterology Volume: 59 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2012 May-Jun |
Date Detail:
|
Created Date: 2012-04-03 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
|
Languages: eng Pagination: 947-50 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prognostic predictors of patients with carcinoma of the gastric cardia.
Next Document: Radical Endoscopic Resection is Unsuitable for Most Synchronous, Multiple and Early Gastric Cancers.