| Biopsy assessment of fifty hearts during transplantation. | |
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MedLine Citation:
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PMID: 3540459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was to evaluate myocardial protection during the transportation of human donor hearts stored at 4 degrees C in crystalloid cardioplegic solution. Biopsies were performed on 50 donor hearts before excision and at four subsequent time intervals during transplantation. Quantitative birefringence measurements on cryostat sections of the left ventricular biopsy specimens were used to assess myocardial function. Fifteen donor hearts had poor birefringence assessments before excision, and 67% received inotropic support after implantation; 22 deteriorated during transportation, and 50% received inotropic support; 13 were unchanged throughout the procedure, and none required inotropic support. This study demonstrates the need for improved protection of donor hearts during transportation and recommends the use of rigorous criteria in the selection of these hearts. |
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Authors:
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S Darracott-Cankovíc; D Wheeldon; R Cory-Pearce; J Wallwork; T A English |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of thoracic and cardiovascular surgery Volume: 93 ISSN: 0022-5223 ISO Abbreviation: J. Thorac. Cardiovasc. Surg. Publication Date: 1987 Jan |
Date Detail:
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Created Date: 1987-02-10 Completed Date: 1987-02-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0376343 Medline TA: J Thorac Cardiovasc Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 95-102 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Biopsy, Needle Birefringence Cold Temperature Heart Diseases / mortality Heart Transplantation* Humans Myocardium / pathology* Organ Preservation / methods Postoperative Period |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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