Document Detail


Biophysics of radiofrequency ablation.
MedLine Citation:
PMID:  21175403     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Radiofrequency (RF) ablation is a treatment modality that kills unwanted tissue by heat. Starting with cardiac arrhythmia treatment in the 1980s, RF ablation has found clinical application in a number of diseases, and is now the treatment of choice for certain types of cardiac arrhythmia and certain cancers. During RF ablation, an electrode is inserted into or steered intravascularly to the target tissue region under medical imaging guidance. Then, a tissue volume surrounding the electrode is destroyed by heating via RF electric current. This paper reviews the biophysics of tissue heating during RF ablation. Effects of electrical tissue conductivity and its change with temperature are discussed. Procedures and devices specific for cancer treatment and for arrhythmia treatment are presented with a brief discussion of additional clinical applications.
Authors:
Dieter Haemmerich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical reviews in biomedical engineering     Volume:  38     ISSN:  0278-940X     ISO Abbreviation:  Crit Rev Biomed Eng     Publication Date:  2010  
Date Detail:
Created Date:  2010-12-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8208627     Medline TA:  Crit Rev Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  53-63     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA. haemmer@musc.edu
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