| Biopharming to increase bioactive peptides in rice seed. | |
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MedLine Citation:
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PMID: 18727558 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The production of high-value pharmaceutical proteins and peptides in transgenic plants is an attractive and economically feasible alternative to conventional mammalian cell, yeast, and bacterial systems. In contrast to vegetative tissues, rice seeds allow higher accumulation of recombinant proteins and long-term stable storage. Rice is not only consumed as a staple food by a majority of the world's population, but is also used as a model monocot for biotechnological manipulation. Daily oral consumption of transgenic rice seeds that accumulate high concentrations of food-derived or synthetic bioactive peptides can be expected to provide a safe, reliable, and consistent oral delivery system that would contribute to the promotion of human health care. |
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Authors:
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Lijun Yang; Yuhya Wakasa; Fumio Takaiwa |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of AOAC International Volume: 91 ISSN: 1060-3271 ISO Abbreviation: J AOAC Int Publication Date: 2008 Jul-Aug |
Date Detail:
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Created Date: 2008-08-27 Completed Date: 2008-09-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9215446 Medline TA: J AOAC Int Country: United States |
Other Details:
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Languages: eng Pagination: 957-64 Citation Subset: IM |
Affiliation:
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Transgenic Crop Research and Development Center, National Institute of Agrobiological Sciences, Kannondai 2-1-2, Tsukuba Ibaraki 305-8602, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Agriculture Animals Humans Oryza sativa / chemistry*, growth & development Peptides / chemistry, pharmacology Plant Proteins / biosynthesis, chemistry*, pharmacology Plants, Genetically Modified / chemistry*, growth & development Seeds / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Peptides; 0/Plant Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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