| Biomimetic scaffolds: implications for craniofacial regeneration. | |
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MedLine Citation:
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PMID: 22337428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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With the advancement in stem cell research and material science, tissue regeneration has been evolved from scientific hypothesis to clinical reality and thus will have a great potential in regenerating craniofacial tissue. In this approach, scaffold plays an essential role in tissue regeneration by recruiting host regenerative cells or enhancing adhesion, proliferation and matrix production of seeded cells, and eventual formation of the desired tissue type. Moreover, incorporation of biomimesis concept into scaffold design and manufacture will further enhance the quality and function of regenerated tissues. This article summarizes new developments of biomimetic scaffolds including the biomimesis of extracellular matrix, cell-matrix interaction, and tissue-regenerative signaling. |
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Authors:
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Jie Yuan; Yilin Cao; Wei Liu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of craniofacial surgery Volume: 23 ISSN: 1536-3732 ISO Abbreviation: J Craniofac Surg Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-02-16 Completed Date: 2012-07-24 Revised Date: 2013-04-05 |
Medline Journal Info:
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Nlm Unique ID: 9010410 Medline TA: J Craniofac Surg Country: United States |
Other Details:
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Languages: eng Pagination: 294-7 Citation Subset: D |
Affiliation:
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Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Tissue Engineering Key Laboratory, Shanghai Jiao Tong University School of Medicine, Shanghai, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acid Sequence Biomechanics Biomimetic Materials / chemistry* Bone Marrow Cells / physiology Bone Matrix / physiology Bone Regeneration / physiology* Bone Substitutes / chemistry Calcium Phosphates / chemistry Cell Adhesion / physiology Cell Differentiation / physiology Cell Proliferation Cell-Matrix Junctions / physiology Chitosan / chemistry Collagen / chemistry Durapatite / chemistry Extracellular Matrix / physiology Facial Bones / surgery* Humans Intercellular Signaling Peptides and Proteins / therapeutic use Oligopeptides / chemistry Osteogenesis / physiology Reconstructive Surgical Procedures / methods* Signal Transduction / physiology Skull / surgery* Stromal Cells / physiology Surface Properties Tissue Engineering / methods* Tissue Scaffolds* |
| Chemical | |
Reg. No./Substance:
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0/Bone Substitutes; 0/Calcium Phosphates; 0/Intercellular Signaling Peptides and Proteins; 0/Oligopeptides; 1306-06-5/Durapatite; 9007-34-5/Collagen; 9012-76-4/Chitosan; 97Z1WI3NDX/calcium phosphate; 99896-85-2/arginyl-glycyl-aspartic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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