Document Detail


A Biomimetic Approach to Lanthionines.
MedLine Citation:
PMID:  22176606     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The asymmetric sulfa-Michael additions of appropriately protected l- and d-cysteine derivatives to new chiral dehydroamino acid derivatives have been developed as key steps in the synthesis of biologically important cysteine derivatives, such as lanthionine (Lan) and β-methyllanthionine (MeLan), which are unusual bis-α-amino acids found in the emerging lantibiotics such as nisin.
Authors:
Carlos Aydillo; Alberto Avenoza; Jesús H Busto; Gonzalo Jiménez-Osés; Jesús M Peregrina; María M Zurbano
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-16
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Departamento de Química, Universidad de La Rioja, Centro de Investigación en Síntesis Química, U.A.-C.S.I.C., E-26006 Logroño, Spain.
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