Document Detail


Biomedical study on combined effects of simulated weightlessness and emergent depressurization of spacecraft.
MedLine Citation:
PMID:  11712548     Owner:  NASA     Status:  MEDLINE    
Abstract/OtherAbstract:
Cabin emergent depressurization (CED) may occur in spacecraft during manned space flight. The purpose of this paper was to study the combined effects of simulated weightlessness (SW) and CED factors on humans and animals. It was found that the amplitude of T wave of human electrocardiograms (ECG) significantly decreased in bed rest and hypoxia compared with the control condition (P<0.05), and that suspension with pure O2 induced severer edema in the lungs of rats than that in only a pure O2 environment. SW and pure O2 caused middle ear congestion and decreased the barofunction during pressure changes. These results indicate that human response to CED factors become more serious under SW because of the blood redistribution.
Authors:
T D Yang; R G Zhang; C M Wang; H W Fu; B L Zhang; J X Zhang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in space research : the official journal of the Committee on Space Research (COSPAR)     Volume:  23     ISSN:  0273-1177     ISO Abbreviation:  Adv Space Res     Publication Date:  1999  
Date Detail:
Created Date:  2001-11-16     Completed Date:  2002-01-30     Revised Date:  2007-04-16    
Medline Journal Info:
Nlm Unique ID:  9878935     Medline TA:  Adv Space Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2049-52     Citation Subset:  S    
Copyright Information:
c1999 COSPAR. Published by Elsevier Science Ltd.
Affiliation:
Institute of Space Medico-Engineering, Beijing P.O. Box 5104, 100094, P.R. China.
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MeSH Terms
Descriptor/Qualifier:
Aerospace Medicine
Animals
Anoxia / physiopathology*
Barotrauma / etiology,  physiopathology
Bed Rest
Decompression / adverse effects*
Electrocardiography
Fluid Shifts / physiology*
Humans
Lung / pathology*,  ultrastructure
Male
Microscopy, Electron
Oxygen / adverse effects*
Oxygen Inhalation Therapy
Pulmonary Edema / etiology,  physiopathology
Rats
Space Suits
Weightlessness Simulation / adverse effects*
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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