Document Detail

Biomedical results of the Skylab Program.
MedLine Citation:
PMID:  11977284     Owner:  NASA     Status:  MEDLINE    
Skylab, the fourth in a logical sequence of USA manned space flight projects following Mercury, Gemini and Apollo, presented life scientists with their first opportunity for an in-depth study of man's response to the space environment. Extensive medical investigations were undertaken to increase our understanding of man's adaptation to the space environment and his readaptation to gravity upon return to earth. The flight durations of the three Skylab missions were progressively increased from 28 days to 59 days and, finally, 84 days. The results of these investigations of the various body systems clearly demonstrated that man can adapt to zero gravity and perform useful work during long-duration space flight. However, definite changes (some unexpected) in the vestibular, cardiovascular, musculo-skeletal, renal and electrolyte areas were documented. The most significant were: the occurrence of space motion sickness early in the missions; diminished orthostatic tolerance, both in-flight and post-flight; moderate losses of calcium, phosphorus and nitrogen; and decreased tolerance for exercise post-flight. The mechanisms responsible for these physiological responses must be understood and, if necessary, effective countermeasures developed before man can endure unlimited exposure to space flight.
E L Michel; R S Johnston; L F Dietlein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Life sciences and space research     Volume:  14     ISSN:  0075-9422     ISO Abbreviation:  Life Sci Space Res     Publication Date:  1976  
Date Detail:
Created Date:  2002-04-27     Completed Date:  2002-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1250331     Medline TA:  Life Sci Space Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  3-18     Citation Subset:  S    
Lyndon B. Johnson Space Center, National Aeronautics and Space Administration, Houston, Texas, USA.
Space Flight Mission:
Flight Experiment; Skylab Project; long duration; manned
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MeSH Terms
Adaptation, Physiological*
Bone Demineralization, Pathologic / physiopathology,  prevention & control
Cardiovascular Deconditioning
Erythrocyte Volume
Fluid Shifts / physiology
Lower Body Negative Pressure
Muscle, Skeletal / physiology
Plasma Volume
Space Flight*
Space Motion Sickness / physiopathology,  prevention & control
Water-Electrolyte Balance / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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