Document Detail


Biomedical applications of distally controlled magnetic nanoparticles.
MedLine Citation:
PMID:  19564057     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nano-sized magnetic particles are increasingly being used across a wide spectrum of biomedical fields. Upon functionalization to enable specific binding, magnetic particles and their targets can be conveniently positioned in vitro and in vivo by the distal application of magnetic fields. Furthermore, such particles can be magnetically heated after reaching their in vivo targets, thus inducing localized cell death that has a considerable therapeutic value in, for instance, cancer therapy. In this context, innovative biomedical research has produced novel applications that have exciting clinical potential. Such applications include magnetically enhanced transfection, magnetically assisted gene therapy, magnetically induced hyperthermia and magnetic-force-based tissue engineering, and the principles and utilities of these applications will be discussed here.
Authors:
José Luis Corchero; Antonio Villaverde
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-06-27
Journal Detail:
Title:  Trends in biotechnology     Volume:  27     ISSN:  1879-3096     ISO Abbreviation:  Trends Biotechnol.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-27     Completed Date:  2009-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8310903     Medline TA:  Trends Biotechnol     Country:  England    
Other Details:
Languages:  eng     Pagination:  468-76     Citation Subset:  IM    
Affiliation:
CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Bellaterra, 08196 Barcelona, Spain.
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MeSH Terms
Descriptor/Qualifier:
Biomedical Research / trends*
Biomedical Technology / methods*
Humans
Magnetics*
Nanoparticles*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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