| Biomechanics of pressure ulcer in body tissues interacting with external forces during locomotion. | |
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MedLine Citation:
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PMID: 20415590 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Forces acting on the body via various external surfaces during locomotion are needed to support the body under gravity, control posture, and overcome inertia. Examples include the forces acting on the body via the seating surfaces during wheelchair propulsion, the forces acting on the plantar foot tissues via the insole during gait, and the forces acting on the residual-limb tissues via the prosthetic socket during various movement activities. Excessive exposure to unwarranted stresses at the body-support interfaces could lead to tissue breakdowns commonly known as pressure ulcers, often presented as deep-tissue injuries around bony prominences or as surface damage on the skin. In this article, we review the literature that describes how the involved tissues respond to epidermal loading, taking into account both experimental and computational findings from in vivo and in vitro studies. In particular, we discuss related literature about internal tissue deformation and stresses, microcirculatory responses, and histological, cellular, and molecular observations. |
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Authors:
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Arthur F T Mak; Ming Zhang; Eric W C Tam |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annual review of biomedical engineering Volume: 12 ISSN: 1545-4274 ISO Abbreviation: Annu Rev Biomed Eng Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-12 Completed Date: 2010-10-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883581 Medline TA: Annu Rev Biomed Eng Country: United States |
Other Details:
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Languages: eng Pagination: 29-53 Citation Subset: IM |
Affiliation:
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Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. arthur.mak@inet.polyu.edu.hk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biomechanics Computer Simulation Female Humans Locomotion / physiology* Mice Pressure Ulcer / etiology, pathology, physiopathology*, prevention & control Prostheses and Implants / adverse effects* Rats Reperfusion Injury / physiopathology* Stress, Mechanical |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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