Document Detail

Biomarkers to Diagnose Early Arthritis in Patients With Psoriasis.
MedLine Citation:
PMID:  25429195     Owner:  NLM     Status:  Publisher    
BACKGROUND: Psoriatic arthritis is a potentially destructive, inflammatory joint disease that affects 20% to 30% of patients with psoriasis. Psoriasis precedes the onset of joint inflammation by approximately 10 years, providing a unique opportunity to intervene and prevent or delay onset of musculoskeletal manifestations. The emergence of sensitive imaging modalities and cellular biomarkers may facilitate early identification of patients with psoriasis who have subclinical joint disease and might help stratify patients with an early onset of arthritis.
METHODS: The translational studies described herein are focused on the development of cellular biomarkers identified with flow cytometry and cell culture techniques in patients with psoriasis and psoriatic arthritis.
RESULTS AND CONCLUSION: The combination of power Doppler ultrasound imaging and cellular biomarkers (ie, CD16 and dendritic cell specific transmembrane protein) to diagnose early psoriatic arthritis and to stratify patients with established psoriatic arthritis provides a new opportunity to optimize treatment outcomes in this potentially disabling disease.
Ya-Hui Grace Chiu; Christopher T Ritchlin
Related Documents :
25147945 - Csf biomarkers and neuropsychological profiles in patients with cerebral small-vessel d...
15352595 - Do the morphological characteristics of arteriovenous malformations affect the results ...
25381725 - Prevalence of spondyloarthritis symptom in inflammatory bowel disease patients: a quest...
25477265 - Elevated erythropoietin and cytokines levels are related to impaired reticulocyte matur...
24035165 - Effects of valsartan versus amlodipine in diabetic hypertensive patients with or withou...
20864785 - Craniopharyngioma in a patient with acromegaly due to a pituitary macroadenoma.
Publication Detail:
Journal Detail:
Title:  Psoriasis forum / National Psoriasis Foundation     Volume:  18     ISSN:  1089-3504     ISO Abbreviation:  Psoriasis Forum     Publication Date:  2012  
Date Detail:
Created Date:  2014-11-27     Completed Date:  -     Revised Date:  2014-11-28    
Medline Journal Info:
Nlm Unique ID:  9890949     Medline TA:  Psoriasis Forum     Country:  -    
Other Details:
Languages:  ENG     Pagination:  2-10     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Longitudinal Stability of Phonological and Surface Subtypes of Developmental Dyslexia.
Next Document:  Meta-analysis comparing same-day versus delayed vitrectomy clinical outcomes for intravitreal retain...