| Biomarkers and predictors of restorative therapy effects after stroke. | |
| | |
MedLine Citation:
|
PMID: 23299824 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Many restorative therapies that promote brain repair are under development. Stroke is very heterogeneous, highlighting the need to identify target populations and to understand intersubject differences in treatment response. Several neuroimaging measures have shown promise as biomarkers and predictors, including measures of structure and function, in gray matter and white matter. The choice of biomarker and predictor can differ with the content of therapy and with the population under study, for example, contralesional hemisphere measures may be of particular importance in patients with more severe injury. Studies of training effects in healthy subjects provide insights useful to brain repair. Limitations of published studies include a focus on chronic stroke, however the brain is most galvanized to respond to restorative therapies in the early days after stroke. Multimodal approaches might be the most robust approach for stratifying patients and so for optimizing prescription of restorative therapies after stroke. |
| | |
Authors:
|
Erin Burke; Steven C Cramer |
Related Documents
:
|
15222274 - An overview of anticoagulants, antiplatelet agents, and the combination in patients wit... 19804534 - Clinical guidelines and off-license recombinant activated factor vii: content, use, and... 12032404 - Distal deep venous thrombosis in a hemophilia a patient with inhibitor and severe infec... 23637004 - Venous thromboembolism in patients with prior stroke. 21181034 - Humoral immune response of patients bitten by the snake bothrops erythromelas. 6886784 - Gram-negative bacillary meningitis in neurosurgical patients. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Current neurology and neuroscience reports Volume: 13 ISSN: 1534-6293 ISO Abbreviation: Curr Neurol Neurosci Rep Publication Date: 2013 Feb |
Date Detail:
|
Created Date: 2013-01-09 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100931790 Medline TA: Curr Neurol Neurosci Rep Country: United States |
Other Details:
|
Languages: eng Pagination: 329 Citation Subset: IM |
Affiliation:
|
Department of Anatomy & Neurobiology, University of California, Irvine, CA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Aspirin and clopidogrel for prevention of ischemic stroke.
Next Document: TLR4 activity protects against hepatocellular tumorigenesis and progression via regulating the expre...