Document Detail

Biomarkers of ovulation, endometrial receptivity, fertilisation, implantation and early pregnancy progression.
MedLine Citation:
PMID:  17061969     Owner:  NLM     Status:  MEDLINE    
Increasing interest in early preconception and periconception exposures and human developmental outcomes has led to studies that monitor subjects from before conception to gestation, birth and childhood. Monitoring ovulation, endometrial receptivity, fertilisation, implantation and gestation requires the non-invasive collection of biological information and samples, and the measurement of biochemical and biological markers (biomarkers) that are associated with the aforementioned physiological events. This paper describes some of the key features of biomarkers needed for epidemiological studies, identifies some existing and potential biomarkers and available measurement devices, and suggests some directions for identification and development of new biomarkers that might be employed in longitudinal studies involving the analysis of female reproductive function and of embryonic development.
Kenneth L Campbell; John C Rockett
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatric and perinatal epidemiology     Volume:  20 Suppl 1     ISSN:  0269-5022     ISO Abbreviation:  Paediatr Perinat Epidemiol     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-25     Completed Date:  2007-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8709766     Medline TA:  Paediatr Perinat Epidemiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  13-25     Citation Subset:  IM    
Department of Biology, University of Massachusetts Boston, Boston, MA 02125-3393, USA.
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MeSH Terms
Biological Markers / analysis*
Embryo Implantation / physiology*
Endometrium / physiology*
Epidemiologic Studies
Fertilization / physiology*
Ovulation / physiology*
Pregnancy / physiology*
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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