| Biomarkers of the intake of dietary polyphenols: strengths, limitations and application in nutrition research. | |
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MedLine Citation:
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PMID: 17666146 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In order to establish firm evidence for the health effects of dietary polyphenol consumption, it is essential to have quantitative information regarding their dietary intake. The usefulness of the current methods, which rely mainly on the assessment of polyphenol intake using food records and food composition tables, is limited as they fail to assess total intake accurately. This review highlights the problems associated with such methods with regard to polyphenol-intake predictions. We suggest that the development of biological biomarkers, measured in both blood and urine, are essential for making accurate estimates of polyphenol intake. However, the relationship between dietary intakes and nutritional biomarkers are often highly complex. This review identifies the criteria that must be considered in the development of such biomarkers. In addition, we provide an assessment of the limited number of potential biomarkers of polyphenol intake currently available. |
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Authors:
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Jeremy P E Spencer; Manal M Abd El Mohsen; Ann-Marie Minihane; John C Mathers |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2007-08-01 |
Journal Detail:
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Title: The British journal of nutrition Volume: 99 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2007-12-18 Completed Date: 2008-05-16 Revised Date: 2009-04-16 |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
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Languages: eng Pagination: 12-22 Citation Subset: IM |
Affiliation:
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School of Chemistry, Food and Pharmacy, University of Reading, Whiteknights, Reading RG6 6AP, UK. j.p.e.spencer@reading.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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analysis,
blood,
urine Diet* Diet Surveys Flavonoids / administration & dosage, analysis*, blood, metabolism, urine Humans Hydroxybenzoic Acids / analysis, blood, urine Nutrition Assessment Phenols / administration & dosage, analysis*, metabolism Research Design |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Flavonoids; 0/Hydroxybenzoic Acids; 0/Phenols; 0/polyphenols; 29656-58-4/phenolic acid |
| Comments/Corrections | |
Comment In:
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Br J Nutr. 2009 Jan;101(1):148
[PMID:
18782464
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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