Document Detail

Biomarkers in acute aortic dissection and other aortic syndromes.
MedLine Citation:
PMID:  21029872     Owner:  NLM     Status:  MEDLINE    
Acute aortic syndromes have an incidence of >30 per million per annum and a high mortality without definitive treatment. Survival may relate to the speed of diagnosis. Although pain is the most common symptom, there is a large fraction of patients in whom the diagnosis may be mistaken or overlooked. Currently, a high index of clinical suspicion is the chief prompt that diverts a patient into a definitive algorithm of imaging investigations. Although there is no point-of-care biochemical test that can be reliably used to positively identify dissection, biomarkers are available that could accelerate the diagnostic pathway and thereby expedite treatment.
Aaron M Ranasinghe; Robert S Bonser
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  56     ISSN:  1558-3597     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-29     Completed Date:  2010-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1535-41     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom.
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MeSH Terms
Acute Disease
Aneurysm, Dissecting / blood*,  diagnosis*,  therapy
Aortic Aneurysm / blood*,  diagnosis*,  therapy
Biological Markers / blood
C-Reactive Protein / metabolism
Elastin / blood
Myosin Heavy Chains / blood
Reg. No./Substance:
0/Biological Markers; 0/Myosin Heavy Chains; 9007-41-4/C-Reactive Protein; 9007-58-3/Elastin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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