Document Detail

Biomarkers for diagnosis in thoracic aortic disease: CON.
MedLine Citation:
PMID:  20452530     Owner:  NLM     Status:  MEDLINE    
The fundamental requirements for a meaningful biomarker have not been met in the prediction of the aneurysm trait, the progression of the aneurysm disease state, or the prevention of catastrophic aortic complications. Aortic aneurysm is a worthy opponent on all fronts, and clinicians should continue actively to evaluate all potential diagnostic and therapeutic adjuncts with high levels of scientific scrutiny and rigor, so that the understanding and management of this disease process evolves in a complementary, rather than duplicative, manner. In the meantime, proteomics, genomics, and metabolomics continue to represent a muse of sorts in scientific circles, but clinicians are responsible for verifying the relevance and meaningful application of its postulates as they apply to individual patients within the context of efficient and effective global health care delivery.
Emily A Farkas
Publication Detail:
Type:  Comment; Journal Article; Review    
Journal Detail:
Title:  Cardiology clinics     Volume:  28     ISSN:  1558-2264     ISO Abbreviation:  Cardiol Clin     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-09-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8300331     Medline TA:  Cardiol Clin     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  213-20     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Department of Surgery, Cardiothoracic Surgery, Saint Louis University School of Medicine, 3635 Vista Avenue, 8th Floor Des Loges Towers, St Louis, MO 63110, USA.
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MeSH Terms
Aortic Aneurysm, Thoracic / diagnosis*,  genetics,  metabolism
Biological Markers / analysis*
Diagnosis, Differential
Genetic Testing / methods
Reproducibility of Results
Severity of Illness Index
Reg. No./Substance:
0/Biological Markers
Comment On:
Cardiol Clin. 2010 May;28(2):207-11   [PMID:  20452529 ]
Comment In:
Cardiol Clin. 2010 May;28(2):221-2   [PMID:  20452531 ]

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