| Biomarkers for alcohol use and abuse--a summary. | |
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MedLine Citation:
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PMID: 19006989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Clinicians can use several biochemical measurements to objectively assess patients' current or past alcohol use. However, none of these currently available biomarkers-including measures of various liver enzymes and blood volume--are ideal. Several more experimental markers hold promise for measuring acute alcohol consumption and relapse. These include certain alcohol byproducts, such as acetaldehyde, ethyl glucuronide (EtG), and fatty acid ethyl esters (FAEE), as well as two measures of sialic acid, a carbohydrate that appears to be altered in alcoholics. Some progress has been made in finding markers that predict people's genetic predisposition to alcoholism, such as genetic differences in several neurotransmitters, including beta-endorphin and gamma-aminobutryic acid (GABA). |
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Authors:
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Karen Peterson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism Volume: 28 ISSN: 1535-7414 ISO Abbreviation: Alcohol Res Health Publication Date: 2004-2005 |
Date Detail:
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Created Date: 2008-11-14 Completed Date: 2008-12-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100900708 Medline TA: Alcohol Res Health Country: United States |
Other Details:
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Languages: eng Pagination: 30-7 Citation Subset: IM |
Affiliation:
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Research Policy and Special Programs Branch, National Institute on Alcohol Abuse and Alcoholism's Office of Scientific Affairs, Bethesda, Maryland, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alanine Transaminase
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blood Alcoholism / blood* Aspartate Aminotransferases / blood Biological Markers Humans N-Acetylneuraminic Acid / blood gamma-Glutamyltransferase / blood |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 131-48-6/N-Acetylneuraminic Acid; EC 2.3.2.2/gamma-Glutamyltransferase; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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