| Biology and pathology of the placenta in relation to antiphospholipid antibody-associated pregnancy failure. | |
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MedLine Citation:
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PMID: 12413055 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The placenta is a complex organ composed of maternal and foetal components whose anatomy and function is often greatly simplified in order to explain a range of presumed placenta-related pregnancy complications. Since one of the major roles of the placenta is its materno-foetal transfer function, abnormalities at the materno-foetal interface may be responsible for a range of pregnancy complications manifesting from the first through third trimesters according to the severity of the pathological process in each case. This article reviews some aspects of abnormal early placental development and its consequences, with particular regard to recurrent pregnancy failure and obstetric complications in association with primary antiphospholipid antibody syndrome. |
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Authors:
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N J Sebire; L Regan; R Rai |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Lupus Volume: 11 ISSN: 0961-2033 ISO Abbreviation: Lupus Publication Date: 2002 |
Date Detail:
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Created Date: 2002-11-04 Completed Date: 2003-03-28 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9204265 Medline TA: Lupus Country: England |
Other Details:
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Languages: eng Pagination: 641-3 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Faculty of Medicine, Imperial College School of Medicine, St Mary's Hospital, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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etiology*,
pathology,
physiopathology* Antiphospholipid Syndrome / complications* Female Humans Placenta / pathology*, physiopathology* Pregnancy Pregnancy Complications* |
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