| Biology of cholesteatoma: Special considerations in pediatric patients. | |
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MedLine Citation:
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PMID: 22264818 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Cholesteatoma is a unique pathologic condition of the temporal bone characterized by migration of keratinized squamous epithelium positioned into the middle ear and mastoid cavity. The exact pathogenic molecular mechanisms behind the formation and propagation of cholesteatoma remain unclear. This review will aim to define the classification of cholesteatomas, review the most accepted pathogenesis theories, describe the inherent molecular mechanisms dictating the hyperproliferative nature of cholesteatoma keratinocytes, and explore innate biological differences between pediatric and adult cholesteatoma. |
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Authors:
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Diego A Preciado |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-19 |
Journal Detail:
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Title: International journal of pediatric otorhinolaryngology Volume: - ISSN: 1872-8464 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003603 Medline TA: Int J Pediatr Otorhinolaryngol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Ireland Ltd. |
Affiliation:
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Division of Pediatric Otolaryngology, Children's National Medical Center, George Washington University School of Medicine, 111 Michigan Av NW, Washington, DC 20010, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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