| Biology of arteriovenous fistula failure. | |
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MedLine Citation:
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PMID: 17514619 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although arteriovenous (AV) fistulae are the preferred form of dialysis access, they continue to have significant problems with both early and late failures. Despite the magnitude of the clinical problem, however, there are unfortunately no effective therapies for AV fistula failure. We believe that this inability to intervene is partly due to a lack of understanding about the pathology and pathogenesis of AV fistula failure. Therefore, in the current review we will initially explore novel concepts about the pathology and pathogenesis of AV fistula failure. This information will then be used to suggest potential therapeutic interventions for this important, yet unmet clinical need. Finally, we will end with a brief description of some state-of-the-art clinical trials that are attempting to apply some of these novel therapeutic concepts to the recalcitrant clinical problem of AV fistula failure. |
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Authors:
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Prabir Roy-Chaudhury; Lawrence M Spergel; Anatole Besarab; Arif Asif; Pietro Ravani |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of nephrology Volume: 20 ISSN: 1121-8428 ISO Abbreviation: J. Nephrol. Publication Date: 2007 Mar-Apr |
Date Detail:
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Created Date: 2007-05-21 Completed Date: 2007-07-31 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9012268 Medline TA: J Nephrol Country: Italy |
Other Details:
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Languages: eng Pagination: 150-63 Citation Subset: IM |
Affiliation:
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Division of Nephrology and Hypertension, University of Cincinnati, Cincinnati, Ohio 45267-0585, USA. Prabir.roychaudhury@uc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Arteriovenous Shunt, Surgical / adverse effects* Clinical Trials as Topic Humans Kidney Failure, Chronic / therapy* Renal Dialysis* / instrumentation Treatment Failure |
| Grant Support | |
ID/Acronym/Agency:
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R01 DK061689/DK/NIDDK NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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