| Biology of aortic aneurysms and dissections. | |
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MedLine Citation:
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PMID: 21979117 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The biology of aortic aneurysm and dissection has evolved to where we now understand the genetic implications of changes in extracellular matrix proteins, smooth muscle cells, and growth factors and how they affect aortic wall homeostasis. These predeterminants are influenced by smoking, hypertension, and atherosclerosis, and the result in an inflammatory response coupled to an accelerated proteolytic cascade that disrupts both elastin and collagen in the aortic wall. |
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Authors:
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Joseph S Fernandez-Moure; Daynene Vykoukal; Mark G Davies |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methodist DeBakey cardiovascular journal Volume: 7 ISSN: 1947-6108 ISO Abbreviation: Methodist Debakey Cardiovasc J Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-10-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101508600 Medline TA: Methodist Debakey Cardiovasc J Country: United States |
Other Details:
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Languages: eng Pagination: 2-7 Citation Subset: IM |
Affiliation:
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Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, Texas. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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