Document Detail


Biological risk of older adults with visual impairments.
MedLine Citation:
PMID:  21437562     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To investigate whether biological markers of health differ among older adults with visual impairment compared to those with normal vision.
DESIGN: We use data from the National Health and Nutrition Examination Survey (1999 - 2006) to investigate clinically defined at-risk levels for 10 biological markers.
SETTING: Survey participants were non-institutionalized.
PARTICIPANTS: Nationally representative (U.S.) sample of older adults age 65 and older, categorized as having blindness (20/200 or worse), low vision (20/40 to 20/100) or normal vision (better than 20/40). Intervention: Separate binary logistic regressions (one for each biomarker, with two at-risk cut points for BMI: obese and underweight) were computed to determine the odds of having at-risk levels of each biomarker.
MEASUREMENTS: Biomarkers included: systolic and diastolic blood pressure, high-density lipoprotein, low-density lipoprotein (LDL) cholesterol, total cholesterol, glycated hemoglobin, body mass index (BMI), fasting triglycerides, C-reactive protein, and plasma homocysteine.
RESULTS: Older adults who were blind were more likely to have high-risk levels of LDL cholesterol, homocysteine, and to be underweight (BMI>18.5). Similarly, older adults with LV were more likely to have high-risk levels of homocysteine compared to older adults with normal vision.
CONCLUSION: As several of the high-risk biomarkers associated with visual impairment were diet-related, our results suggest the importance of nutrition and diet programs aimed towards educating older people who are visually impaired.
Authors:
B A Steinman; S Vasunilashorn
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of nutrition, health & aging     Volume:  15     ISSN:  1760-4788     ISO Abbreviation:  J Nutr Health Aging     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-25     Completed Date:  2011-05-18     Revised Date:  2011-06-15    
Medline Journal Info:
Nlm Unique ID:  100893366     Medline TA:  J Nutr Health Aging     Country:  France    
Other Details:
Languages:  eng     Pagination:  296-302     Citation Subset:  IM    
Affiliation:
University of Southern California, Southern California, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Biological Markers / analysis*
Blindness / blood,  epidemiology,  etiology
Blood Pressure / physiology
Body Mass Index
C-Reactive Protein / metabolism
Diet*
Female
Health Surveys*
Homocysteine / blood
Humans
Lipid Metabolism / physiology
Logistic Models
Male
Risk Factors
Vision Disorders / blood,  epidemiology*,  etiology
Vision, Low / blood,  epidemiology,  etiology
Grant Support
ID/Acronym/Agency:
T32AG0037/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Biological Markers; 454-28-4/Homocysteine; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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