Document Detail


Biological responses of Lumbriculus variegatus exposed to fluoranthene-spiked sediment.
MedLine Citation:
PMID:  11910457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lumbriculus variegatus was used as a bioassay organism to examine the impact of the sediment-associated polycyclic aromatic hydrocarbon (PAH) fluoranthene on behavior, reproduction, and toxicokinetics. The number of worms increased between the beginning and end of the experiment at 59 microg x g(-1) fluoranthene, but at the next higher treatment (108 microg x g(-1)) the number of worms found was lower and not different from the control. Worms exposed to 95 microg x g(-1) also exhibited increased reproduction when fed a yeast-cerophyl-trout chow mixture. On a total biomass basis, only the 95 microg x g(-1) exposure with food exhibited a statistically significant increase over the nonfed control. Evaluation of reproduction at the two highest treatments was compromised by a brief aeration failure 2 days before the end of the experiment. The behavioral responses were followed as changes in biological burial rate (sediment reworking rate) of a 137Cs-labeled marker layer. The biological burial rate increased toward a plateau as the concentration increased from the control (3.9 microg x g(-1) dry weight total PAH) to 355 microg x g(-1) dry weight fluoranthene in sediment. The aeration failure had minimal impact on the determination of reworking rate because all the data for the rate determination were collected prior to the aeration failure. Uptake and elimination rates declined with increasing treatment concentration across the range of fluoranthene concentrations, 59-355 microg x g(-1) dry weight sediment. The disconnect between the increasing biological burial rates and the decreasing toxicokinetics rates with increasing exposure concentration demonstrates that the toxicokinetic processes are dominated by uptake and elimination to interstitial water. The bioaccumulation factor (concentration in the organisms on a wet weight basis divided by the concentration in sediment on a dry weight basis) ranged from 0.92 to 1.88 on day 10 and declined to a range of 0.52 to 0.99 on day 28 with the lowest value at the highest dose.
Authors:
P F Landrum; M L Gedeon; G A Burton; M S Greenberg; C D Rowland
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Archives of environmental contamination and toxicology     Volume:  42     ISSN:  0090-4341     ISO Abbreviation:  Arch. Environ. Contam. Toxicol.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-03-22     Completed Date:  2002-05-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0357245     Medline TA:  Arch Environ Contam Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  292-302     Citation Subset:  IM    
Affiliation:
Great Lakes Environmental Research Laboratory, 2205 Commonwealth Blvd., Ann Arbor, Michigan 48105, USA. landrum@glerl.noaa.gov
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MeSH Terms
Descriptor/Qualifier:
Animals
Environmental Exposure*
Enzyme Inhibitors / adverse effects*,  pharmacokinetics
Fluorenes / adverse effects*,  pharmacokinetics
Geologic Sediments / chemistry
Movement
Oligochaeta / physiology*
Population Dynamics
Reproduction / drug effects*
Soil Pollutants / adverse effects*,  pharmacokinetics
Tissue Distribution
Chemical
Reg. No./Substance:
0/Enzyme Inhibitors; 0/Fluorenes; 0/Soil Pollutants; 206-44-0/fluoranthene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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