Document Detail

Biological monitoring of acrylonitrile exposure.
MedLine Citation:
PMID:  9546096     Owner:  NLM     Status:  MEDLINE    
This study reports the results obtained with the environmental and biological monitoring of 34 workers exposed to acrylonitrile (ACN). Occupational exposure was monitored during 8-h work shifts with both active and diffusive personal samplers which yielded comparable results. The median exposure was 78 micrograms/m3. The ACN concentration in urine collected at the end of the work shifts correlated significantly with the environmental exposure. The ACN concentration in the pre-shift urine samples (median 3.6 micrograms/l) was lower than that found in the post-shift samples (median 10.9 micrograms/l), but higher than in the urine of non-exposed people (median 0.45 microgram/l). Smoking is an important confounding factor in monitoring exposure to ACN. The ACN concentration in urine provides reliable information about occupational and non-occupational exposure to ACN. Aspects of the mechanism of ACN excretion in urine are also discussed.
L Perbellini; A Ganzi; G Venturi; M Cerpelloni; F Brugnone
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Giornale italiano di medicina del lavoro ed ergonomia     Volume:  20     ISSN:  1592-7830     ISO Abbreviation:  G Ital Med Lav Ergon     Publication Date:    1998 Jan-Mar
Date Detail:
Created Date:  1998-05-26     Completed Date:  1998-05-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9712708     Medline TA:  G Ital Med Lav Ergon     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  10-4     Citation Subset:  IM    
Institute of Occupational Medicine, University of Verona, Italy.
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MeSH Terms
Acrylonitrile / toxicity*,  urine
Chromatography, Gas
Data Interpretation, Statistical
Environmental Monitoring
Occupational Exposure*
Time Factors
Reg. No./Substance:

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