Document Detail


Biological effects of shock waves: induction of arrhythmia in piglet hearts.
MedLine Citation:
PMID:  8059489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During lithotripsy by electrohydraulic or electromagnetic lithotripters, the application of extracorporeal shock waves has to be synchronized with the electrocardiogram to reduce the induction of arrhythmias. The relation between the refractory period of the cardiac cycle and arrhythmia induction by shock waves, and the underlying mechanism have so far not been examined. In this experiment, the cardiac response to shock waves administered at 20 kV by an electrohydraulic lithotripter was assessed in nine piglets. The focus was positioned 5, 10 and 15 cm caudal to the apex of the left ventricle, and in some piglets also at the apex. The interval following the R-wave was determined during which the heart was refractory to shock wave stimulation by either single discharges or shock-wave bursts, i.e., groups of discharges separated by 10 ms intervals. This mechanical refractory period was compared to its electrical counterpart, which was determined by transvenous intracardiac atrial stimulation. As a result, mechanical refractory periods following the R-wave were at 5 cm distance 60 ms for single discharges and 70 ms for bursts (medians; range 10-180 ms); both stimulation modes were highly correlated (r = 0.88). While a similar result was obtained with the focus positioned directly at the cardiac apex, at 10 cm distance from it, bursts elicited a cardiac response significantly more often (in nine vs. two piglets). At 15 cm distance, no response was obtained at all. Both mechanical and electrical atrial refractory periods were in a similar range.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
M Delius; E Hoffmann; G Steinbeck; P Conzen
Related Documents :
3591969 - Hemorrhagic shock impairs myocardial cell volume regulation and membrane integrity in d...
18972629 - Levosimendan as rescue therapy in severe cardiogenic shock after st-elevation myocardia...
23438629 - Myocardial abscess secondary to staphylococcal septicemia: diagnosis with 3d echocardio...
14522739 - Body mass index and preinfarction angina in elderly patients with acute myocardial infa...
3421879 - A case of cardiovascular collapse due to adrenal insufficiency.
2928649 - Direct effects of purified staphylococcal toxic shock syndrome toxin 1 on myocardial fu...
15378129 - Current medical management of chronic stable angina.
14516529 - 3d-cardiac-pet. a recommendable clinical alternative to 2d-cardiac-pet?
3768069 - Inhibition of thromboxane synthetase by the imidazole derivative 3-(1h-imidazol-1-yl-me...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  20     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  1994  
Date Detail:
Created Date:  1994-09-13     Completed Date:  1994-09-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  279-85     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Munich, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Animals
Arrhythmias, Cardiac / etiology*
Electric Stimulation
Electrocardiography
Lithotripsy / adverse effects*
Swine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Optimum acoustic frequency for focused ultrasound surgery.
Next Document:  Mouse lung damage from exposure to 30 kHz ultrasound.