| Biological characteristics of neuroblastoma with spontaneous tumor reduction: a case report. | |
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MedLine Citation:
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PMID: 7623238 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors examined the biological characteristics of a neuroblastoma with spontaneous tumor reduction. A 6-month-old boy with a pelvic neuroblastoma underwent surgical extirpation of the tumor 1 month after diagnosis. The size of the tumor reduced spontaneously while he was awaiting operation. The low proliferative activity of the tumor cells and the presence of apoptosis in the tumor tissue were shown by an immunohistochemical method using anti-PCNA antibody and a DNA fragmentation analysis, respectively. These results suggest that the spontaneous tumor reduction seen in this patient may well be caused by the overwhelming apoptosis of tumor cells. |
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Authors:
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M Iwata; T Koshinaga; I Okabe; Y Kurosu; M Esumi |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 30 ISSN: 0022-3468 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 1995 May |
Date Detail:
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Created Date: 1995-08-31 Completed Date: 1995-08-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 722-3 Citation Subset: IM |
Affiliation:
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First Department of Surgery, Nihon University School of Medicine, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Apoptosis* DNA Damage DNA, Neoplasm Humans Infant Male Neoplasm Regression, Spontaneous / physiopathology* Neuroblastoma / genetics, physiopathology* Pelvic Neoplasms / genetics, physiopathology* Proliferating Cell Nuclear Antigen |
| Chemical | |
Reg. No./Substance:
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0/DNA, Neoplasm; 0/Proliferating Cell Nuclear Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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