Document Detail


Biological characteristics of neuroblastoma with spontaneous tumor reduction: a case report.
MedLine Citation:
PMID:  7623238     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors examined the biological characteristics of a neuroblastoma with spontaneous tumor reduction. A 6-month-old boy with a pelvic neuroblastoma underwent surgical extirpation of the tumor 1 month after diagnosis. The size of the tumor reduced spontaneously while he was awaiting operation. The low proliferative activity of the tumor cells and the presence of apoptosis in the tumor tissue were shown by an immunohistochemical method using anti-PCNA antibody and a DNA fragmentation analysis, respectively. These results suggest that the spontaneous tumor reduction seen in this patient may well be caused by the overwhelming apoptosis of tumor cells.
Authors:
M Iwata; T Koshinaga; I Okabe; Y Kurosu; M Esumi
Related Documents :
21684758 - Prognostic significance of il-8-stat-3 pathway in astrocytomas: correlation with il-6, ...
22123728 - Malignant brenner tumor of the ovary with transformation to trabecular carcinoid: an im...
20556608 - Predictive value of tumor proliferative indices in periampullary cancers: ki-67, mitoti...
8342118 - Measurement of the proliferative activity of three different sublines of the dunning ra...
19497588 - Metabolic alterations in the peritumoral brain in cases of meningiomas: 1h-mrs study.
23474568 - Solid pseudopapillary tumor of the pancreas in a child: imaging findings with diffusion...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  30     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-08-31     Completed Date:  1995-08-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  722-3     Citation Subset:  IM    
Affiliation:
First Department of Surgery, Nihon University School of Medicine, Tokyo, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Apoptosis*
DNA Damage
DNA, Neoplasm
Humans
Infant
Male
Neoplasm Regression, Spontaneous / physiopathology*
Neuroblastoma / genetics,  physiopathology*
Pelvic Neoplasms / genetics,  physiopathology*
Proliferating Cell Nuclear Antigen
Chemical
Reg. No./Substance:
0/DNA, Neoplasm; 0/Proliferating Cell Nuclear Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Neuroblastoma in infants aged less than 6 months: is more aggressive treatment necessary? A report f...
Next Document:  Frantz's tumor (solid and cystic tumor of the pancreas) with liver metastasis: successful treatment ...