Document Detail

Biokinetic models for radiocaesium and its progeny.
MedLine Citation:
PMID:  23296405     Owner:  NLM     Status:  Publisher    
The International Commission on Radiological Protection (ICRP) is preparing a series of reports that will provide updated biokinetic and dosimetric models and dose coefficients for occupational intake of radionuclides. The biokinetic modelling scheme continues a trend in ICRP reports towards physiologically realistic descriptions of the time-dependent behaviour of absorbed radionuclides and their radioactive progeny. This paper proposes systemic biokinetic models for caesium isotopes and their ingrowing chain members and examines the dosimetric implications of the proposed models. Comparisons of D(68) = tissue dose per unit input to blood based on current ICRP models for workers (ICRP Publication 68, 1994) with D(P) = corresponding values based on the proposed biokinetic models (but using the dosimetry models of Publication 68) yields the following ranges of the ratios D(P):D(68) for the tissues addressed in Publication 68: 0.5-25 for (130)Cs (T(1/2) = 29.2 min), 0.6-9.5 for (134m)Cs (2.9 h), 0.7-1.7 for (131)Cs (9.69 d), 0.7-1.1 for (134)Cs (2.06 y), 0.5-1.9 for (137)Cs (30.2 y) and 0.2-3.7 for (135)Cs (2.3 × 10(6) y). The large differences in the derived dose coefficients for some tissues and caesium isotopes, particularly short-lived isotopes, result mainly from differences in predictions of the time-dependent distributions of caesium in the body. For example, the proposed model and the current ICRP model for occupational intake of caesium predict peak kidney contents of ∼22% and ∼0.4%, respectively, following intravenous injection of stable caesium. Based on the proposed models for caesium and its progeny, the only dosimetrically significant chain members of caesium isotopes with half-life ≥10 min are (137m)Ba, which represents 32-85% of the estimated tissue doses from injected (137)Cs, and (134)Cs, which represents 4-53% of the estimated tissue doses from injected (134m)Cs.
R W Leggett
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-07
Journal Detail:
Title:  Journal of radiological protection : official journal of the Society for Radiological Protection     Volume:  33     ISSN:  1361-6498     ISO Abbreviation:  J Radiol Prot     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809257     Medline TA:  J Radiol Prot     Country:  -    
Other Details:
Languages:  ENG     Pagination:  123-140     Citation Subset:  -    
Environmental Sciences Division, Building 5700, Room O101, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
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