Document Detail

Bioinformatics: from genome data to biological knowledge.
MedLine Citation:
PMID:  9425655     Owner:  NLM     Status:  MEDLINE    
Recently, molecular biologists have sequenced about a dozen bacterial genomes and the first eukaryotic genome. We can now obtain answers to detailed questions about the complete set of genes of an organism. Bioinformatics methods are increasingly used for attaching biological knowledge to long lists of genes, assigning genes to biological pathways, comparing the gene sets of different species, identifying specificity factors, and describing sets of highly conserved proteins common to all domains of life. Substantial progress has recently been made in the availability of primary and added-value databases, in the development of algorithms and of network information services for genome analysis. The pharmaceutical industry has greatly benefited from the accumulation of sequence data through the identification of targets and candidates for the development of drugs, vaccines, diagnostic markers and therapeutic proteins.
M A Andrade; C Sander
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in biotechnology     Volume:  8     ISSN:  0958-1669     ISO Abbreviation:  Curr. Opin. Biotechnol.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-02-02     Completed Date:  1998-02-02     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9100492     Medline TA:  Curr Opin Biotechnol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  675-83     Citation Subset:  IM    
EMBL-EBI, Cambridge, UK.
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MeSH Terms
Databases, Factual
Gene Expression
Medical Informatics*
Proteins / genetics,  physiology
RNA, Messenger / genetics
Reg. No./Substance:
0/Proteins; 0/RNA, Messenger

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