Document Detail

Biofilms in Chronic Wounds and the Potential Role of Negative Pressure Wound Therapy: An Integrative Review.
MedLine Citation:
PMID:  23354367     Owner:  NLM     Status:  Publisher    
Biofilms are communities of microbes that exist in a variety of environments. The extracellular substances secreted by biofilms make them difficult to eradicate, giving the bacterial community in the biofilm a resistance advantage over freefloating (planktonic) microbes. Biofilms are particularly problematic in chronic wounds because of their resistance to conventional therapies and tendency to delay healing. Multimodal strategies to combat wound biofilms are necessary, including wound debridement, antimicrobial treatment, and continued disruption of biofilms. Negative pressure wound therapy with irrigation or instillation may lower the bacterial burden in chronic wounds and prevent the biofilm formation. This article provides an overview of biofilms and evolving strategies to counteract them.
Beth Hawkins Bradley; Muriel Cunningham
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-24
Journal Detail:
Title:  Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society / WOCN     Volume:  -     ISSN:  1528-3976     ISO Abbreviation:  J Wound Ostomy Continence Nurs     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9435679     Medline TA:  J Wound Ostomy Continence Nurs     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Beth Hawkins Bradley, MN, RN, CWOCN, Vice President, Clinical Education, Innovative Therapies, Inc., Gaithersburg, Maryland. Muriel Cunningham, MEd, is an independent consultant and was compensated by Innovative Therapies Inc.
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