| Bioengineering of bacterial magnetic particles and their applications in biotechnology. | |
| | |
MedLine Citation:
|
PMID: 21171958 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Magnetic particles have attracted much attention for their versatile uses in biotechnology, especially in medical applications. The major advantage of magnetic particles is that they can be easily manipulated by magnetic forces. Magnetotactic bacteria synthesize nano-sized biomagnetites, otherwise known as bacterial magnetic particles (BacMPs) that are individually enveloped by a lipid bilayer membrane. The mechanisms of BacMP synthesis have been analyzed by genomic, proteomic, and bioinformatic approaches. Based on those studies in Magnetospirillum magneticum AMB-1, functional nanomaterials have been designed and produced. Through genetic engineering, functional proteins such as enzymes, antibodies, and receptors have been successfully displayed on BacMPs. These functional BacMPs have been utilized in various biosensors and bio-separation processes. Here, recent papers and patents for bioengineering of BacMPs and their applications in biotechnology are reviewed. The elucidation of the mechanism of magnetic particle synthesis has provided a roadmap for the design of novel biomaterials that can play useful roles in multiple disciplinary fields. |
| | |
Authors:
|
Tomoko Yoshino; Yoshiaki Maeda; Tadashi Matsunag |
Related Documents
:
|
3399588 - Psychiatric morbidity in patients with clinically isolated lesions of the type seen in ... 18831988 - A method for localizing microelectrode trajectories in the macaque brain using mri. 6143338 - Computed axial brain tomography in long-term benzodiazepine users. 3973148 - Mr imaging of brain stem gliomas. 18290048 - On some bayesian/regularization methods for image restoration. 18796658 - Clinical utility of dual-energy ct in the evaluation of solitary pulmonary nodules: ini... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Recent patents on biotechnology Volume: 4 ISSN: 2212-4012 ISO Abbreviation: Recent Pat Biotechnol Publication Date: 2010 Nov |
Date Detail:
|
Created Date: 2010-12-21 Completed Date: 2011-03-24 Revised Date: 2011-11-10 |
Medline Journal Info:
|
Nlm Unique ID: 101309942 Medline TA: Recent Pat Biotechnol Country: United Arab Emirates |
Other Details:
|
Languages: eng Pagination: 214-25 Citation Subset: IM |
Affiliation:
|
Department of Biotechnology, Tokyo University of Agriculture and Technology, 2-24-16, Naka-cho, Koganei, Tokyo, 184-8588, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antibodies
/
metabolism Automation, Laboratory Bacterial Proteins / metabolism* Bioengineering* Biosensing Techniques Biotechnology* Carrier Proteins / metabolism Computational Biology Gene Fusion Lipid Bilayers / metabolism Magnetospirillum / metabolism* Membrane Proteins / metabolism* Patents as Topic Protein Engineering Proteomics |
| Chemical | |
Reg. No./Substance:
|
0/Antibodies; 0/Bacterial Proteins; 0/Carrier Proteins; 0/Lipid Bilayers; 0/Membrane Proteins; 0/MpsA protein, Magnetospirillum sp. |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Development of yeast molecular display systems focused on therapeutic proteins, enzymes, and foods: ...
Next Document: Applications of yeast cell-surface display in bio-refinery.