Document Detail

Bioencapsulation within synthetic polymers (Part 2): non-sol-gel protein-polymer biocomposites.
MedLine Citation:
PMID:  11058788     Owner:  NLM     Status:  MEDLINE    
Since the introduction of sol-gel bioencapsulation and the demonstration that biological function can be incorporated into, and preserved within, polymer matrices, a number of alternative polymers have been used to immobilize proteins. Various enzymes have been trapped in such diverse polymers as epoxy-amine resins, polyvinyl plastics, polyurethane foams and silicone elastomers. Together with sol-gel encapsulates, these biocomposites represent a powerful approach for immobilizing biological materials for applications as biosensors and biocatalysts, and hold promise as bioactive, fouling-resistant polymers for environmental, food and medical uses. Although still at the developmental stage, these biocomposites promise to revolutionize the whole arena of high-performance bioimmobilization.
I Gill; A Ballesteros
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Trends in biotechnology     Volume:  18     ISSN:  0167-7799     ISO Abbreviation:  Trends Biotechnol.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2000-12-01     Completed Date:  2001-01-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8310903     Medline TA:  Trends Biotechnol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  469-79     Citation Subset:  IM    
Biotransformations Department, Biotechnology Center of Excellence, Roche Vitamins Inc., Building 102, Nutley, NJ 07110-1199, USA.
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MeSH Terms
Biocompatible Materials / chemistry*
Biosensing Techniques
Drug Compounding / methods*
Drug Stability
Epoxy Resins
Polymers / chemical synthesis
Reg. No./Substance:
0/Biocompatible Materials; 0/Capsules; 0/Epoxy Resins; 0/Gels; 0/Plastics; 0/Polymers; 0/Proteins; 0/Silicones

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