Document Detail

Bioelectrical impedance vs. four-compartment model to assess body fat change in overweight adults.
MedLine Citation:
PMID:  17228035     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The Tanita TBF-305 body fat analyzer is marketed for home and clinical use and is based on the principles of leg-to-leg bioelectrical impedance analysis (BIA). Few studies have investigated the ability of leg-to-leg BIA to detect change in percentage fat mass (%FM) over time. Our objective was to determine the ability of leg-to-leg BIA vs. the four-compartment (4C) model to detect small changes in %FM in overweight adults. RESEARCH METHODS AND PROCEDURES: Thirty-eight overweight adults (BMI, 25.0 to 29.9 kg/m2; age, 18 to 44 years; 31 women) participated in a 6-month, randomized, double-blind, placebo-controlled study of a nutritional supplement. Body composition was measured at 0 and 6 months using the Tanita TBF-305 body fat analyzer [using equations derived by the manufacturer (%FM(T-Man)) and by Jebb et al. (%FM(T-Jebb))] and the 4C model (%FM(4C)). RESULTS: Subjects in the experimental group lost 0.9%FM(4C) (p = 0.03), a loss that did not reach significance using leg-to-leg BIA (0.6%FM(T-Man), p = 0.151; 0.6%FM(T-Jebb), p = 0.144). We observed large standard deviations (SDs) in the mean difference in %FM between the 4C model and the Tanita(Manufacturer) (2.5%) and Tanita(Jebb) (2.2%). Ten subjects fell outside +/-1 SD of the mean differences at 0 and 6 months; those individuals were younger and shorter than those within +/-1 SD. DISCUSSION: Leg-to-leg BIA performed reasonably well in predicting decreases in %FM in this group of overweight adults but resulted in wide SDs vs. %FM(4C) in individuals. Cross-sectional determinations of %FM of overweight individuals using leg-to-leg BIA should be interpreted with caution.
Laura E Chouinard; Dale A Schoeller; Abigail C Watras; R Randall Clark; Rachel N Close; Andrea C Buchholz
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obesity (Silver Spring, Md.)     Volume:  15     ISSN:  1930-7381     ISO Abbreviation:  Obesity (Silver Spring)     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-17     Completed Date:  2007-03-20     Revised Date:  2008-01-21    
Medline Journal Info:
Nlm Unique ID:  101264860     Medline TA:  Obesity (Silver Spring)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  85-92     Citation Subset:  IM    
Department of Family Relations and Applied Nutrition, University of Guelph, 50 Stone Road E, Guelph, Ontario, Canada N1G 2W1.
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MeSH Terms
Absorptiometry, Photon / methods
Adipose Tissue / metabolism*
Body Composition / physiology*
Double-Blind Method
Electric Impedance*
Indicator Dilution Techniques
Models, Biological*
Obesity / diagnosis,  physiopathology
Overweight / physiology*
Reproducibility of Results
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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