Document Detail


Biodegradation of acrylic based resins: A review.
MedLine Citation:
PMID:  20189238     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The development of different types of materials with application in dentistry is an area of intense growth and research, due to its importance in oral health. Among the different materials there are the acrylic based resins that have been extensively used either in restorations or in dentures. The objective of this manuscript was to review the acrylic based resins biodegradation phenomena. Specific attention was given to the causes and consequences of materials degradation under the oral environment. DATA AND SOURCES: Information from scientific full papers, reviews or abstracts published from 1963 to date were included in the review. Published material was searched in dental literature using general and specialist databases, like the PubMED database. STUDY SELECTION: Published studies regarding the description of biodegradation mechanisms, in vitro and in vivo release experiments and cell based studies conducted on acrylic based resins or their components were evaluated. Studies related to the effect of biodegradation on the physical and mechanical properties of the materials were also analyzed. CONCLUSIONS: Different factors such as saliva characteristics, chewing or thermal and chemical dietary changes may be responsible for the biodegradation of acrylic based resins. Release of potential toxic compounds from the material and change on their physical and mechanical properties are the major consequences of biodegradation. Increasing concern arises from potential toxic effects of biodegradation products under clinical application thus justifying an intensive research in this area.
Authors:
Ana F Bettencourt; Cristina B Neves; Marise S de Almeida; L?dia M Pinheiro; Sofia Arantes e Oliveira; Lu?s P Lopes; Matilde F Castro
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-02-26
Journal Detail:
Title:  Dental materials : official publication of the Academy of Dental Materials     Volume:  26     ISSN:  1879-0097     ISO Abbreviation:  Dent Mater     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-03-24     Completed Date:  2010-06-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508040     Medline TA:  Dent Mater     Country:  England    
Other Details:
Languages:  eng     Pagination:  e171-80     Citation Subset:  D    
Copyright Information:
2010 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Research Institute for Medicines and Pharmaceutical Sciences, University of Lisbon, Portugal. asimao@ff.ul.pt
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MeSH Terms
Descriptor/Qualifier:
Acrylic Resins / chemistry*,  metabolism*,  toxicity
Animals
Biotransformation
Dental Stress Analysis
Humans
Hydrolysis
Methylmethacrylates / chemistry
Chemical
Reg. No./Substance:
0/Acrylic Resins; 0/Methylmethacrylates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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