Document Detail

Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering.
MedLine Citation:
PMID:  20361991     Owner:  NLM     Status:  MEDLINE    
Bone tissue engineering is an alternative strategy to generate bone utilizing a combination of biomaterials and cells. Biomaterials that mimic the structure and composition of bone tissues at nanoscale are important for the development of bone tissue engineering applications. Natural or biopolymer-based composites containing chitin, chitosan, or collagen have advantages such as biocompatibility, biodegradability that are essential for bone tissue engineering. The inclusion of nanoparticles of hydroxyapatite (one of the most widely used bioceramic materials) into the biopolymer matrix improves the mechanical properties and incorporates the nanotopographic features that mimic the nanostructure of bone. This review summarizes the recent work on the development of biocomposites containing natural polymers with hydroxyapatite particles suitable for use in bone defects/bone regeneration.
Maddela Swetha; Kolli Sahithi; Ambigapathi Moorthi; Narasimhan Srinivasan; Kumarasamy Ramasamy; Nagarajan Selvamurugan
Publication Detail:
Type:  Journal Article; Review     Date:  2010-03-31
Journal Detail:
Title:  International journal of biological macromolecules     Volume:  47     ISSN:  1879-0003     ISO Abbreviation:  Int. J. Biol. Macromol.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-05-24     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909578     Medline TA:  Int J Biol Macromol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1-4     Citation Subset:  IM    
Copyright Information:
(c) 2010 Elsevier B.V. All rights reserved.
Department of Biotechnology, School of Bioengineering, SRM University, Kattankulathur 603 203. Tamil Nadu, India.
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MeSH Terms
Bone Regeneration
Bone Substitutes*
Tissue Engineering / methods*
Reg. No./Substance:
0/Bone Substitutes; 1306-06-5/Durapatite; 1398-61-4/Chitin; 9007-34-5/Collagen; 9012-76-4/Chitosan

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