Document Detail


Biochemistry, physiology, and complications of blood doping: facts and speculation.
MedLine Citation:
PMID:  16769597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Competition is a natural part of human nature. Techniques and substances employed to enhance athletic performance and to achieve unfair success in sport have a long history, and there has been little knowledge or acceptance of potential harmful effects. Among doping practices, blood doping has become an integral part of endurance sport disciplines over the past decade. The definition of blood doping includes methods or substances administered for non-medical reasons to healthy athletes for improving aerobic performance. It includes all means aimed at producing an increased or more efficient mechanism of oxygen transport and delivery to peripheral tissues and muscles. The aim of this review is to discuss the biochemistry, physiology, and complications of blood doping and to provide an update on current antidoping policies.
Authors:
Giuseppe Lippi; Massimo Franchini; Gian Luca Salvagno; Gian Cesare Guidi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical reviews in clinical laboratory sciences     Volume:  43     ISSN:  1040-8363     ISO Abbreviation:  Crit Rev Clin Lab Sci     Publication Date:  2006  
Date Detail:
Created Date:  2006-06-13     Completed Date:  2006-10-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8914816     Medline TA:  Crit Rev Clin Lab Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  349-91     Citation Subset:  IM    
Affiliation:
Dipartimento di Scienze Morfologico-Biomediche, Istituto di Chimica e Microscopia Clinica, Università Degli Studi di Verona, Verona, Italy.
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MeSH Terms
Descriptor/Qualifier:
Blood Substitutes / therapeutic use
Blood Transfusion / methods
Doping in Sports*
Erythropoietin / metabolism*
Erythropoietin, Recombinant / metabolism*
Fluorocarbons / metabolism,  therapeutic use
Gene Therapy / methods*
Hemoglobins / metabolism,  therapeutic use
Humans
Muscle, Skeletal / physiology*
Physical Endurance / physiology*
Sports / physiology*
Substance Abuse Detection / methods*
Chemical
Reg. No./Substance:
0/Blood Substitutes; 0/Erythropoietin, Recombinant; 0/Fluorocarbons; 0/Hemoglobins; 0/erythropoiesis stimulating protein, human; 11096-26-7/Erythropoietin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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